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Table 5 Genes horizontally transferred from eukaryotic genomes to Legionella genomes

From: Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease

L. pneumophila

L. longbeachae

L. micdadei

L. hackeliae

L. fallonii (LLAP10)

Name

Product [domain]

lpg0095/lpp0109

llo3322

lmi1217

lha1000

lfa0120

 

cytosolic IMP-GMP specific 5'-nucleotidase

lpg0422 a/lpp0489

llo2801

 

lha1522

lfa2690

 

glucoamylase

lpg0971/lpp1033

     

ecto-ATP diphosphohydrolase II

lpg1119/lpp1120

llo1016

  

lfa1837

 

map Major acid phosphatase Map (histidine-acid phosphatase)

lpg1155/lpp1157

     

pyruvate decarboxylase

lpg1565/lpp1522

llo0920

 

lha3027

  

thi thiamine biosynthesis protein NMT-1

lpg1675/lpp1647

llo3277

lmi0628

 

lfa1689

purC

phosphoribosylamidoimidazole-succinocarboxamide synthase

lpg1905/lpp1880

llo1247

lmi2007

lha1318

lfa0744

 

putative Apyrase

lpg1950 a/lpp1932

llo1397

   

ralF

RalF, translocated into host cells by the Dot/Icm system

lpg2176 a/lpp2128

  

lha1689

lfa3030

 

sphingosine-1-phosphate lyase I

lpg2556 a/lpp2626

llo2218

    

protein kinase-like

lpg2911

llo1568

  

lfa0029

cysK

cysteine synthase A, O-acetylserine sulfhydrolase A subunit

lpg2917

llo2243

lmi0866

lha0637

lfa1734

 

conserved protein of unknown function [FADPNR domain]

lpg2951/lpp3022

llo0076

lmi3045

lha3116

lfa3723

cysK

cysteine synthase A, O-acetylserine sulfhydrolase A subunit

      

protein of unknown function [SNARE domain]

  

lmi2545

 

lfa1498

 

protein of unknown function [ank domain] [Ras domain] [coiled-coil domain]

 

llo0042

  

lfa0022

 

putative Dipeptidyl-peptidase II

 

llo1314

    

conserved protein of unknown function [Leucine-rich repeat domain]

 

llo1320

lmi2237

lha0011

lfa1070

 

DWF 7-dehydrocholesterol reductase

 

llo1999

    

putative Sphingomyelin phosphodiesterase

 

llo2200

lmi0200

lha3048

lfa0156

 

protein of unknown function [Tubulin-tyrosine ligase domain)

 

llo2329

    

GTP-binding protein ypt1 [Ras small GTPase, Rab type]

 

llo3082

    

protein of unknown function [Mitochondrial substrate carrier]

 

llo3182

 

lha1738

  

phosphoprotein phosphatase

 

llo3288

  

lfa1897

 

protein of unknown function [Ras small GTPase, Rab type]

  

lmi0037

   

protein of unknown function [RhoGAP motif] [coiled-coil]

  

lmi0515

   

protein of unknown function [cAMP-binding domain-like]

  

lmi0854

   

protein of unknown function [Ras GTPase domain]

  

lmi1956

   

putative Adenosine deaminase

  

lmi1981

   

phosphoprotein phosphatase

   

lha0498

  

protein of unknown function [Synaptobrevin]

   

lha0511

  

protein of unknown function

   

lha0998

  

membrane protein of unknown function [Ras small GTPase, Rab type]

   

lha1423

  

protein of unknown function [Cytochrome P450 domain]

   

lha2690

  

membrane protein of unknown function [Ras small GTPase, Rab type]

    

lfa0589

 

endo-1,3(4)-beta-glucanase

    

lfa1399

 

protein of unknown function [H3 methylation by DOT1]

    

lfa1711

 

membrane protein of unknown function [Ras small GTPase, Rab type]

    

lfa2465

 

membrane protein of unknown function [Ras small GTPase, Rab type]

    

lfa2470

 

protein of unknown function [SecA DEAD-like]

  1. aGene encoding a protein that has been demonstrated to be secreted by the Dot/Icm secretion system.