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Table 3 Core of substrates of the Dot/Icm secretion system present in 11 Legionella genomes

From: Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires’ disease

Label Product and associated motif Gene name Amino acid identity a
    L. fallonii L. long. L. micdadeii L. hack
lpg0021/lpp0021 Protein of unknown function [ribosome associated protein]   75 75 68 68
lpg0103/lpp0117 N-terminal acetyltransferase, GNAT family vipF 62 61 50 47
lpg0107/lpp0121 b Conserved protein of unknown function ravC 84 80 72 47
lpg0140/lpp0155 Membrane protein of unknown function cetLP1 53 45 39 36
lpg0376/lpp0443 Protein of unknown function sdhA 60 48 38 38
lpg0405/lpp0471 Protein of unknown function   56 56 50 40
lpg0483/lpp0547 Protein of unknown function [ankyrin]c legA12/ankC 55 49 31 29
lpg1356/lpp1310 Putative Beta-lactamase [Sel1-domain]c[TPR repeat]c EnhC homologue 80 71 67 69
lpg1578/lpp4178 Protein of unknown function   50 37 25 24
lpg1661/lpp1632 Heparan-alpha glucosaminide N-acetyltransferased   60 57 47 48
lpg1663/lpp1634 Protein of unknown function cetLP3 54 44 40 58
lpg1752/lpp1716 Protein of unknown function mavB 41 40 27 26
lpg1907/lpp1882 Membrane protein of unknown function [hydrolases]   54 52 44 49
lpg2300/lpp2248 Protein of unknown function [ankyrin]c legA3/ankH/ankW 81 76 71 75
lpg2322/lpp2270 Protein of unknown function [ankyrin] legA5/ankK 57 51 39 42
lpg2351/lpp2300 Protein of unknown function mavF 56 50 33 33
lpg2359/lpp2308 Protein of unknown function [putative GatB/Yqey domain]c   82 79 73 72
lpg2588/lpp2947 Acid sphingomyelinase-like phosphodiesterase legS1 64 61 54 33
lpg2591/lpp2644 Protein of unknown function ceg33 46 47 34 26
lpg2815/lpp2867 Membrane protein of unknown function mavN 62 64 54 52
lpg2832/lpp2889 Protein of unknown function   72 68 60 62
lpg2888/lpp2947 Membrane protein of unknown function [coiled-coil]c   59 50 34 40
lpg2936/lpp3004 Ribosomal RNA small subunit methyltransferase E   67 67 60 60
lpg2975/lpp3047 Protein of unknown function mavQ 58 57 33 30
  1. aAmino acid identity with respect to L. pneumophila strain Philadelphia. bravC has been erroneously named as lpg0170 in previous publications. cThe motif is present in all orthologues. dHigh prediction for enzymatic activity in all the corresponding orthologues (prediction based on PRIAM EC number). Bold numbers indicate synteny between L. pneumophila genes and the corresponding orthologous gene.