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Table 3 Demographics of animals used in prospective challenge study

From: Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replication

ID

MHC

GZMB

32 week viral load (log10)

Sex

cy0642

M1/M3

G1/G2

5.7

F

cy0643

M1/M3

G1/G2

5.8

F

cy0646

M1/M3

G2/G5

3.1

F

cy0648

M1/M3

G1/G4

2.3

F

cy0649

M1/M3

G1/G2

5.5

F

cy0651

M1/M3

G2/G3

4.9

F

cy0652

M1/M3

G4/G4

3.9

F

cy0654

M1/M3

G2/G5

5.7

F

  1. Eight MHC-identical (M1/M3) Mauritian cynomolgus macaques were assembled into a cohort to prospectively test the influence of granzyme B genetics on MHC-associated control of SIV replication. Animal identifier, MHC genotype, 32 week viral loads (log10 viral RNA copies per milliliter of plasma), and sex are shown for each animal. The granzyme B genotype for each animal is shown.