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Table 2 Genes within candidate control-modifying loci

From: Whole genome sequencing of SIV-infected macaques identifies candidate loci that may contribute to host control of virus replication

Chromosome

Gene

Ensembl coordinates [[27]]

Length (bp)

Variants

T-cell function [[29]]

3

GRM3

130400561-130623515

222,954

-

-

7

NYNRIN

87296239-87307068

10,829

-

-

CBLN3

87324653-87327636

2,983

-

-

KHNYN

87328804-87336472

7,668

-

-

SDR39U1

87337848-87340858

3,010

-

-

CMA1

87390195-87392979

2,784

-

-

CTSG

87449456-87452155

2,699

-

-

GZMH

87479687-87482876

3,189

-

+

GZMB

87509950-87513263

3,313

-

+

STXBP6

87705567-87964506

258,939

111

-

SNORD37

88705465-88705530

65

-

-

NOVA1

89330662-89479984

149,322

1

-

8

EBF2

25963548-26009524

45,976

3

-

9

ATE1

121374357-121553580

179,223

47

-

NSMCE4A

121573109-121591667

18,558

2

-

TACC2

121664364-121871454

207,090

12

-

10

MKKS

43683348-43712508

29,160

34

-

14

FOLH1

87860094-87925735

65,641

-

-

TRIM64

87975789-87981217

5,428

-

-

TRIM49

87997993-88004315

6,322

1

-

NAALAD2

88578293-88633487

55,194

3

-

CHORDC1

88642339-88664787

22,448

-

-

  1. Among the seven candidate loci identified through whole genome sequencing analysis, six candidates contained coding genes (as determined using Ensembl annotations). Across these six regions, a total of 22 genes were identified, 9 of which contained control-segregating variants. For these 22 genes, the corresponding chromosome, coordinates, gene length, and number of control-segregating variants occurring within the gene are shown.
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Genome Biology

ISSN: 1474-760X

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