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Table 2 Prognostically unfavorable chromosomal regions of loss in diffuse low-grade gliomas

From: Spatial and temporal evolution of distal 10q deletion, a prognostically unfavorable event in diffuse low-grade gliomas

Chromosome

Start

End

Cytoband

Discovery cohort (%)

Validation cohort (%)

Discovery cohort

Validation cohort

(P-value)

(P-value)

9

24450001

28650000

9p21.3-21.1

21

7

0.039

1

10

112950001

135435000

10q25.2-qter

18

10

0.009

0.041

11

195001

14250000

11p15.5-15.2

13

15

0.0006

1

13

19500001

92550000

13q12.1-31.3

17

13

0.0001

1

22

34350001

51180000

22q12.3-13.33

11

8

0.000004

1

  1. Frequency and P-value in discovery and validation cohorts calculated by log rank test and adjusted for multiple testing by Benjamini Hochberg and Holm Bonferroni, respectively. Positions according to GRCh37/hg19.