New H3K27ac peaks are enriched within the gene bodies of up-regulated genes. (A) DNA methylation profiles and tag density plots for H3K27ac at the promoters of genes containing intronic enhancers (left) and at the locations of intronic enhancers (right). Pie chart shows the percentage of the 310 intergenic enhancers identified within the gene bodies of the up-regulated genes that are intronic or exonic. (B) Genome browser snapshot of the genomic region surrounding the SASH1 gene. The H3K27ac track in green shows an increase in signal within the gene’s intronic regions in DKO1 (light green) relative to HCT116 (dark green).