Figure 3From: Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changesActive histone modifications and RNA polymerase II are drastically reduced at promoters in DKO1 cells. Shown is the percentage DNA methylation (heat bars) and the density of ChIP-seq tags for H3K4me3 (reds), H3K27ac (greens), and RNAPII (blues) surrounding the transcription start sites of promoters that had less than 50% methylation (left) and promoters that had more than 50% methylation in HCT116 cells (right). Light-colored dashed lines represent the marks in DKO1 cells.Back to article page