Figure 2
From: Global loss of DNA methylation uncovers intronic enhancers in genes showing expression changes
Overview of ChIP-seq data in HCT116 and DKO1 cells. Shown is a region of chromosome 6 illustrating the reduction in levels of active marks in DKO1 cells compared with HCT116 cells, for RNAP II (blues), H3K4me3 (reds), H3K27ac (greens), and H3K36me3 (oranges). Dark and light colors represent HCT116 and DKO1 cells, respectively. Although peaks are reduced in height at most sites, some genomic locations do have increases in H3K4me3 (blue boxes) or H3K27ac (red boxes) in DKO1 cells.