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Figure 2 | Genome Biology

Figure 2

From: Comparative sequencing analysis reveals high genomic concordance between matched primary and metastatic colorectal cancer lesions

Figure 2

Phenotypic concordance of mutations. In patient 10, the primary tumor harbors a nonsense mutation not found in the metastatic tumor (A). (B) However, the tumor/normal ratio per exon of coverage on chromosome 5 shows that the exons of APC (red dots) are deleted in the metastatic tumor, yielding identical phenotypic results. Similar results were found for PIK3CA and TP53 (Additional file 2: Figure S2).

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