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Figure 2 | Genome Biology

Figure 2

From: Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine

Figure 2

Somatic aberrations in cancer cell populations. The DNA copy number and number of mutant alleles (red stars) within single cancer cells can be difficult to discern when looking at a whole population of cancer cells. Samples 1-3 on average each have three copies of a particular chromosome, and a variant allele frequency of 0.33, but the collection of cancer cells in each population are vastly different. Single-cell sequencing may be required to elucidate the underlying population structure.

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