Analysis of whole-exome sequencing data on patient S15 and S17 from chemo-resistant relapse vs. primary ovarian cancer dataset. (A) Clustering of somatic mutations in patient S15. (B) Mutation clusters and CP values in S15 primary and relapse. (C) Uniquely identified, compatible S15 primary and relapse subclone evolution tree. (D) Clustering of S17 somatic mutations in patient S17. (E) Mutation clusters and CP values in S17 primary and relapse. (F) Two viable structures for S17 primary, and a sole structure for S17 relapse.