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Figure 8 | Genome Biology

Figure 8

From: Cancer progression modeling using static sample data

Figure 8

Seven key genes (AURKA, PLAU, STAT1, VEGF, CASP3, ESR1, and ERBB2) representing proliferation, tumor invasion/metastasis, immune response, angiogenesis, apoptosis phenotypes, and ER and HER2 signaling, respectively, were mapped onto the two major progression branches of the METABRIC model. For ease of presentation in one plot, the expression level of each gene was normalized into the interval of [0,1]. The small interval between normal and luminal A represents normal-like.

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