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Table 5 Multivariate Cox proportional hazard analyses

From: Genome-wide DNA methylation profiles in progression to in situand invasive carcinoma of the breast with impact on gene transcription and prognosis

 

HR

HR 95% confidence interval

P-value

Training set

   

ER status

1.32

0.62-2.84

0.470

TP53 mutation

1.08

0.48-2.45

0.850

T status (2)

2.14

0.89-5.13

0.088

T status (3 or 4)

1.48

0.47-4.59

0.502

Lymph node status

2.22

0.89-5.51

0.087

Prognostic signature

29.0

9.36-89.9

5.4E-09

TCGA validation

   

ER status

0.87

0.49-1.55

0.639

T status (2)

0.92

0.47-1.82

0.814

T status (3 or 4)

1.14

0.51-2.54

0.749

Lymph node status

2.13

1.14-3.98

0.018

Prognostic signature

2.09

1.21-3.59

0.008

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Genome Biology

ISSN: 1474-760X

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