Figure 4
From: Genome-driven integrated classification of breast cancer validated in over 7,500 samples
Explained variation in gene expression levels of genes contained within TCGA-defined regions of recurrent copy number alteration in breast cancer. Forest plots of the average differences in adjusted R-squared statistics between classifiers (IntClust and PAM50) by study according to genes within loci recurrently amplified (red) or deleted (blue) in breast cancer. Boxes represent point estimates where box size is weighted according to study sample size and horizontal lines depict 95% CIs. Point estimates and confidence intervals are based on bootstrap resampling of 1,000 replicates. Diamonds depict the weighted average difference.