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Figure 4 | Genome Biology

Figure 4

From: Transcriptome sequencing reveals altered long intergenic non-coding RNAs in lung cancer

Figure 4

LCAL expression in lung cancer. (A-C) Coverage maps showing the average expression levels of tumor and normal samples across all three lung cancer cohorts for LCAL1 (A), LCAL5 (B), and LCAL7 (C). Annotated RefSeq (dark blue), Ensembl (red), Human Body Map lncRNAs (brown), and full-length transcripts as determined by 5’ and 3’ RACE in H322M cell line (black) are shown below each plot. (D-F) qPCR validation in an independent cohort of human adenocarcinoma and matched controls and squamous cell carcinoma and matched controls for LCAL1 (D), LCAL5 (E), and LCAL7 (F). Insert tables distinguish `high’ and `low’ expression of LCALs in tumors using the value as denoted by the dotted line.

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