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Figure 7 | Genome Biology

Figure 7

From: Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes

Figure 7

GRα binds a half site in distinct conformation. Hill plot derived from an electrophoretic mobility shift assay describing the fraction of oligonucleotides containing a half site with an adjacent ‘anti-motif’ - that is, the least favorable binding sequence according to the half site motif -(gtacAGAACAtttGTGAGGtcgac) bound at increasing GRα concentrations [4]. The Hill coefficient was computed from the Hill Equation (right) to be 1.080 ± 0.065.

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