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Figure 4 | Genome Biology

Figure 4

From: A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators

Figure 4

A correlogram of eleven variables describing promoter architecture. In the correlogram, there are four measures of GC-content: GC-content in a 1 kb proximal promoter (GC), GC-content in a 20 kbps window around the promoter (GC_big), GC-content in a third codon position (GC3), and the frequency of CpG sites (CpG); there are also four measures describing the number of transcription factor binding sites in promoters: Tfbs1 (Tfbs_length – straight number of Tfbs), Tfbs2 (Tfbs_length_unique – the number of unique Tfbs), Tfbs3 (Tfbs_length_noPol2 – the number of Tfbs excluding PolII), and Tfbs4 (Tfbs_length_unique_noPol2 - the number of unique Tfbs excluding PolII), a measure of methylation (methyl), a signature of digestion by DNASE1 (DNASE1), and the breadth of expression (BoE).

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Genome Biology

ISSN: 1474-760X

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