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Figure 2 | Genome Biology

Figure 2

From: Non-targeted transcription factors motifs are a systemic component of ChIP-seq datasets

Figure 2

Zinger motifs are enriched at the peak maximum of non-zinger ChIP-seq datasets. The enrichment plots display the location of the top scoring motif for each peak relative to the peakMax (the peakMax is at 0) on the x-axis, while the score of the motif is plotted on the y-axis. The adjacent line plots display the fraction of motifs observed in 5 bp increments. The logo reflecting the binding specificity for each zinger appears above the related enrichment plot. (A) CTCF motif predictions from NRF1 ChIP-seq (GM12878 cells). (B) JUN motif predictions from TCF7L2 ChIP-seq (Hct116 cells). (C) GABPA motif predictions from NFKB ChIP-seq (GM19099 cells). (D) THAP11 motif predictions from IRF1 ChIP-seq (K562 cells).

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