Figure 4
From: MBASED: allele-specific expression detection in cancer tissues and cell lines
Summary of ASE extent in the studied samples. (A) Percentage of tested genes declared ASE in one-sample analysis of lung cancer cell lines. (B) Percentage of tested genes declared ASE in one-sample analysis of tissue samples (both tumor and normal). Considerably more genes are found to show ASE in tumor than in normal samples. (C) Tumor-specificity of ASE found in one-sample analysis of tissue samples. All genes found to be ASE in one-sample analysis are broken down into genes that are (a) not tested in a two-sample comparison (due to lack of common sufficiently covered SNVs, gray), (b) found to show ASE in two-sample comparison (red), and (c) not found to show ASE in two-sample comparison (black).