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Figure 1 | Genome Biology

Figure 1

From: Seq and CLIP through the miRNA world

Figure 1

High-throughput methods for sequencing small RNAs and their targets. Conceptual protocols highlighting the differences between the methods for deep sequencing of (a) small RNAs and of (b-e) small RNA targets (PAR-CLIP (b), CLASH (c), HITS-CLIP (d), iCLIP (e)). Ni-NTA, nickel nitrilotriacetic acid; Gu-HCL, guanidine hydrochloride; PNK, polynucleotide kinase.

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