Figure 5

Copy numbers and chromatin immunoprecipitation. (A,B) A heatmap that summarizes correlation between copy numbers and chromatin immunoprecipitation (ChIP) signals of expressed genes in S2-DRSC (A) or Kc167 (B) cell lines. Target proteins for ChIP and modENCODE submission numbers are listed (right side). Columns show autosomal promoter regions (1 kb upstream of transcription start) and gene body regions as indicated. (C,D) ChIP signals of H3K9me2 (C) and SU(HW) (D) at autosome gene bodies are displayed against different copy number classes as boxplots (S2-DRSC cells). Top, middle, and bottom lines of boxes for upper quartile, median, and lower quartile points, respectively. Notches indicate the 95% confidence interval of each median and whiskers display the maximum, or minimum, value within the range of 1.5 times of interquartile distance, respectively. Dots display individual genes within different copy number classes. Pearson’s correlation for r and its significance (P-value). (E,F) ISWI ChIP signal analyzed for X chromosome gene bodies in a male (S2-DRSC; E) and a female (Kc167; F) cell line. TSS, transcription start site.