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Figure 1 | Genome Biology

Figure 1

From: SVA retrotransposon insertion-associated deletion represents a novel mutational mechanism underlying large genomic copy number changes with non-recurrent breakpoints

Figure 1

Location of the breakpoints of the 17 atypical NF1 deletions. At the top is a schematic representation of the NF1 gene and its flanking regions. The relative positions of the genes located within this region are denoted by horizontal black bars. Below, the extents of the 17 NF1 deletions analyzed are indicated by horizontal bars. The centromeric breakpoints of the deletions depicted by red bars are located within SUZ12P. None of these deletions had telomeric breakpoints located within SUZ12. The deletions depicted by blue bars exhibit breakpoints located within NF1-REPa. Two deletions (grey bars) extended beyond the region indicated here in a centromeric direction (indicated by dotted lines). The patient identification numbers are given on the left. cen, centromere; tel, telomere.

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Genome Biology

ISSN: 1474-760X

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