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Table 1 Average correlation across all probes of normalised methylation measurements between relative pairs

From: Contribution of genetic variation to transgenerational inheritance of DNA methylation

Relationship

Pairs (n)

Correlation

Expecteda

MZ twins

67

0.200

h 2

DZ twins

111

0.109

h2/2

Siblings

262b

0.090

h2/2

Parent-Offspring

362b

0.089

h2/2

Mother-Offspring

190

0.097

h2/2

Father-Offspring

172

0.085

h2/2

Parent-Parent

58

0.023

0

Unrelated

187,331b

-0.002

0

  1. aThe expected correlation under an additive genetic model with a heritability of h2.
  2. bThis is the number of quasi-independent pairs as some individuals are represented in multiple pairings.