Figure 4

Imprinting. (A) Methylation levels across all samples, showing imprinting of the gene H13. The height of the bar represents percentage methylation from 0 to 100%. Gray represents missing data. (B) Expression levels of Met measured by RNA-seq. (C) Methylation levels for an allelically methylated region (AMR) in the gene Met measured by RRBS sequencing. Each line represents CpGs in a sequencing read; open circles are unmethylated and filled circles are methylated CpGs. Reads are shown on the Y-axis and the genomic location of CpGs is shown on the X-axis. (D) Traditional bisulfite sequencing (BS) in the Met AMR. Sequences in different bacterial clones are on the Y-axis and the genomic location of CpGs is on the X-axis.