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Figure 1 | Genome Biology

Figure 1

From: Chronic cocaine-regulated epigenomic changes in mouse nucleus accumbens

Figure 1

Chronic cocaine-induced transcriptome in mouse NAc. (A) Cocaine-regulated transcriptomic events versus total events illustrated as percentages (for example, 92 out of 22,000 genes show significant expression changes), which are based on Cuffdiff prediction (see Materials and methods). (B) Gene Ontology (GO) enrichment for differentially spliced genes is illustrated as an enrichment map [26]: each node represents an enriched GO term and its size represents the number of genes; the color intensity of the node represents the statistical significance; the strength of the green lines represents the number of common genes shared between two nodes; the GO terms that are clustered together are circled and summarized with a name. Singletons are not shown; a full list of enriched GO terms is in Additional file 6.

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