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Table 1 Number of real, missing and spurious hotspots identified by different methods applied to simulated data

From: Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies

Method

Real hotspots

Missing hotspots

Spurious hotspots

Sensitivity

False discovery rate

t-test

5

0

8

1.0

0.62

SVA

5

0

0

1.0

0

ICE

0

5

0

0

N/A

LMM-EH

0

5

0

0

N/A

PANAMA

5

0

8

1.0

0.62

NICE

5

0

0

1.0

0

  1. N/A, not applicable.