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Figure 2 | Genome Biology

Figure 2

From: Effectively identifying regulatory hotspots while capturing expression heterogeneity in gene expression studies

Figure 2

eQTL maps for different methods applied to the simulated data. The x-axis corresponds to SNP positions and the y-axis corresponds to the gene positions. The intensity of a point on the plot represents the significance of the association. The diagonal band represents the cis effects and the vertical bands represent hotspots. Blue arrows show the locations of real genetic regulatory hotspots, green arrows indicate missing hotspots and red arrows show spurious hotspots. The eQTL map for the standard t-test (a), SVA (b), ICE (c), LMM-EH (d), PANAMA (e) and NICE (f) are shown.

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