3D-SP correctly classifies MLL leukemia types de novo . (A) Leukemia cell panel used to test 3D-SP. Cell lines are organized by MLL status and leukemia type. (B) Classification results of the test leukemia cell panel by the 3D-SP trained to distinguish between MLL fusion and wt MLL (Figure 1C). Results shown are from de novo classification by the 3D-SP. Matthews Correlation Coefficient (MCC) = 1.0.