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Table 1 Top candidate driver genes in 14 diffuse-type gastric cancers

From: Genomic profile analysis of diffuse-type gastric cancers

Gene Samples, n nsSNVs, n SNVs in splice site, n Indels, n P-value Driver gene score
PIK3CA 5 5 0 0 3.63 × 10−12 9.83
CDH1 5 4 1 1 4.64 × 10−10 8.02
SNRPN 2 2 0 0 1.86 × 10−07 5.60
TP53 2 2 0 0 4.88 × 10−07 5.36
CMKLR1 2 2 0 0 5.33 × 10−07 5.36
CYP2A7 2 2 0 0 1.53 × 10−06 4.99
GUCY1B3 2 2 0 0 1.97 × 10−06 4.99
PAPOLB 2 2 0 0 2.15 × 10−06 4.99
MYH9 3 3 0 0 2.27 × 10−06 4.99
FAM71B 1 2 0 0 2.51 × 10−06 4.99
C10orf90 2 2 0 0 3.76 × 10−06 4.86
AKAP8 2 2 0 0 4.59 × 10−06 4.81
ZC3H12B 2 2 0 0 5.87 × 10−06 4.74
SFTA3 1 1 0 0 6.86 × 10−06 4.70
SENP7 2 2 0 0 7.65 × 10−06 4.68
TMPRSS6 2 2 0 0 8.38 × 10−06 4.67
PAGE2 1 1 0 0 9.94 × 10−06 4.62
  1. For additional driver gene lists, see Additional file 1: Table S9.