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Table 3 Gene expression and methylation correlation

From: DNA methylome profiling of human tissues identifies global and tissue-specific methylation patterns

Gene region

Neg PCCsa

Pos PCCsb

PCCs < -0.5c

PCCs >0.5d

Totale

Global

5,710

4,410

1,713

1,090

10,120

 

56.42%

43.58%

16.93%

10.77%

 

Promoter + CGI

3,048

2,325

618

567

5,373

 

56.73%

43.27%

11.50%

10.55%

 

TSS1500

4,175

4,581

958

1,064

8,756

 

47.68%

52.32%

10.94%

12.15%

 

TSS200

4,157

3,199

979

747

7,356

 

56.51%

43.49%

13.31%

10.15%

 

5’UTR

1,500

1,604

382

442

3,104

 

48.32%

51.68%

12.31%

14.24%

 

1st exon

1,330

1,409

272

357

2,739

 

48.56%

51.44%

9.93%

13.03%

 

Body

5,156

4,620

1,573

1,185

9,776

 

52.74%

47.26%

16.09%

12.12%

 

3’UTR

3,302

3,494

903

854

6,796

 

48.59%

51.41%

13.29%

12.57%

 

Shores

4,534

3,365

1,362

792

7,899

 

57.40%

42.60%

17.24%

10.03%

 

Shelves

2,342

2,201

718

576

4,543

 

51.55%

48.45%

15.80%

12.68%

 
  1. aNegative Pearson Correlation coefficients (PCCs).
  2. bPositive PCCs.
  3. cStrong negative PCCs, smaller than -0.5.
  4. dStrong positive PCCs, larger than 0.5.
  5. eTotal number of tDMRs in named category.