Figure 2
Features of hydroxymethylome in the human brain. (a) Classification of all CpGs in the adult brain according to their hydroxymethylation and methylation frequencies. (b) Fold enrichment of the CpG categories on different genomic elements. hmChigh is enriched in enhancers, exons and introns. (c) The absolute hmC and mC levels at different genomic elements in the adult brain. (d) Fold enrichment of the Fetal > Adult hmCGs, which exhibited higher hmC levels in the fetal brain than in the adult brain, on different genomic elements.