Figure 1

Fibroblast methylation beta values are bimodal and the two modes show different breakdown in terms of CpG islands and genes. Distribution of methylation beta values in type II probes across the genome, partitioned by position relative to (A) CpG islands (with a shore defined by Illumina as less than 2 kb from an annotated CpG island, a shelf as 2 to 4 kb, and open sea as more than 4 kb) and (B) annotated genes.