Regional methylation estimates for samples of Bock data. Smoothed color density representation of regional DNAme estimates of BayMeth, plotted against RRBS methylation levels, where the estimated standard deviation of BayMeth is smaller than 0.15 for bins with more than 20 reads for RRBS and at least a depth of 10 in the SssI control. (a)-(d) Single samples from the original study. The number of bins for each sample is shown at the bottom center of the panels. RRBS, reduced representation bisulfite sequencing.