Regional methylation estimates for IMR-90 chromosome 7. Smoothed color density representation of regional DNAme estimates for BALM, MEDIPS, Batman, BayMeth and BayMeth ignoring SssI information, plotted against WGBS methylation levels for the 75% of bins with the largest depth in the truth (cutoff was 33 reads) where the depth in the SssI control was (27,168]. In addition the y = x line (green dashed line) is shown. Black points indicate outliers. WGBS, whole genome bisulfite sequencing.