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Figure 2 | Genome Biology

Figure 2

From: voom: precision weights unlock linear model analysis tools for RNA-seq read counts

Figure 2

voom mean-variance modeling. (a) Gene-wise square-root residual standard deviations are plotted against average log-count. (b) A functional relation between gene-wise means and variances is given by a robust LOWESS fit to the points. (c) The mean-variance trend enables each observation to map to a square-root standard deviation value using its fitted value for log-count. LOWESS, locally weighted regression.

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