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Figure 4 | Genome Biology

Figure 4

From: Aging of blood can be tracked by DNA methylation changes at just three CpG sites

Figure 4

Age-related DNAm correlates with telomere length. (a) Telomere length of granulocytes was analyzed by flow-FISH in samples from 104 healthy donors (grey), patients with aplastic anemia (AA; red) and dyskeratosis congenita (DKC; blue). (b, c) Age predictions with our epigenetic aging signature demonstrated that several patients with AA or DKC - particularly those with telomere attrition - were predicted to be significantly older than their chronological age (in comparison to age predictions for the validation set in Figure 2f).

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