Figure 3

Three categories of Sm-associated RNAs in Drosophila and human. Different categories of Sm-associated RNAs are color-coded. (a) Drosophila Sm-associated RNAs, with enrichment ratios from all six Sm RIP-seq experiments. For snRNAs with multiple distinct paralogs (U1, U2, U4 and U5), all the reads were pooled for calculation of enrichment ratios. The three U6 paralogs are identical in sequence. See Table S6 in Additional file 1 for assignment of reads to distinct paralogs. U7 was not plotted due to low read coverage. See Table S5 in Additional file 1 for detailed enrichment ratios. (b) Human Sm-associated RNAs. Medians of enrichment ratios were plotted for snRNAs with multiple paralogs. See Table S7 in Additional file 1 for detailed enrichment ratios.