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Table 1 Intron retention ratio is correlated with cassette exon, mutually exclusive exon and intron retention splicing events

From: The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

Alternative splicing event type Number of annotated events in ENSEMBL for all exons (n = 38,911) Number of matched events for exons with 3′SS IR ≥0.10 (n = 6,658) Mean number of matched events in background (1,000 × re-sampling 6,658 exons from 38,911) Permutation P-value
CNE 19,513 2,538 3,338 0.001
CE 8,641 1,936 1,479 0.001
MXE 1,265 294 216 0.001
IR 3,614 749 620 0.001
A3SS 1,249 208 213 0.636
A5SS 1,242 243 213 0.009
  1. Number of alternative splicing event types mapped within 1) all exons in expressed genes and 2) exons having at least 10% of intron retention in their 3′SS, and the mean number of the event types within randomly sampled exon sets of the same size. CNE, constitutive exon; CE, cassette exon; MXE, mutually exclusive exon; IR, intron retention; A3SS, alternative 3′ splice site; A5SS, alternative 5′ splice site.