Skip to main content

Table 1 Intron retention ratio is correlated with cassette exon, mutually exclusive exon and intron retention splicing events

From: The RNA-binding protein hnRNPLL induces a T cell alternative splicing program delineated by differential intron retention in polyadenylated RNA

Alternative splicing event type

Number of annotated events in ENSEMBL for all exons (n = 38,911)

Number of matched events for exons with 3′SS IR ≥0.10 (n = 6,658)

Mean number of matched events in background (1,000 × re-sampling 6,658 exons from 38,911)

Permutation P-value

CNE

19,513

2,538

3,338

0.001

CE

8,641

1,936

1,479

0.001

MXE

1,265

294

216

0.001

IR

3,614

749

620

0.001

A3SS

1,249

208

213

0.636

A5SS

1,242

243

213

0.009

  1. Number of alternative splicing event types mapped within 1) all exons in expressed genes and 2) exons having at least 10% of intron retention in their 3′SS, and the mean number of the event types within randomly sampled exon sets of the same size. CNE, constitutive exon; CE, cassette exon; MXE, mutually exclusive exon; IR, intron retention; A3SS, alternative 3′ splice site; A5SS, alternative 5′ splice site.