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Figure 6 | Genome Biology

Figure 6

From: RNAmotifs: prediction of multivalent RNA motifs that control alternative splicing

Figure 6

RNA splicing maps of multivalent RNA motifs enriched at the exons differentially spliced between adult brain and heart. The RNA splicing maps are shown as described in FigureĀ 2 for a comparison between adult brain and heart splicing. (A) Tetramers enriched at positions corresponding to the standard pattern of RNA maps (enrichment in r 1 and r 2 of exons silenced in the brain, and/or in r 3 of exons enhanced in the brain). These tetramers are predicted to be bound by RBPs with higher expression in the brain compared with the heart. (B) The 10 top ranking tetramers enriched at positions corresponding to the reciprocal pattern of RNA maps (enrichment in r 1 and r 2 of exons enhanced in the brain, and/or in r 3 of exons silenced in the brain). These tetramers are predicted to be bound by RBPs with higher expression in the heart compared to the brain. Nt, nucleotides.

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