The certainty of prediction correlates with measured binding affinities. Prediction certainty is given by GraphProt margins on the y-axis and measured affinities for two sets of PTB aptamers on the x-axis. Fitted linear models and 95% confidence intervals are depicted in blue and dark gray. Binding affinities are given by (A) relative association constants from  and (B) affinities relative to the wild-type (wt) probe from . wt, wild type.