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Table 1 Strongly upregulated RNA-binding proteins identified from nine cancers in humans and their cancer relevant references

From: Dissecting the expression landscape of RNA-binding proteins in human cancers

Associated gene name

Description

References

CCDC124

Coiled-coil domain containing 124

 

CSTF2

Cleavage stimulation factor, 3′ pre-RNA, subunit 2, 64 kDa

[26]

DDX3X

DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked

[27–29]

DKC1

Dyskeratosis congenita 1, dyskerin

[30–32]

EIF1AX

Eukaryotic translation initiation factor 1A, X-linked

 

FAM120C

Family with sequence similarity 120C

 

FLNA

Filamin A, alpha

[33–36]

FMR1

Fragile X mental retardation 1

 

GNL3L

Guanine nucleotide binding protein-like 3 (nucleolar)-like

[37, 38]

GSPT2

G1 to S phase transition 2

 

HNRNPH2

Heterogeneous nuclear ribonucleoprotein H2 (H')

 

HTATSF1

HIV-1 Tat specific factor 1

 

HUWE1

HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase

[39]

LAS1L

LAS1-like (Saccharomyces cerevisiae)

 

MBNL3

Muscleblind-like splicing regulator 3

 

MECP2

Methyl CpG binding protein 2 (Rett syndrome)

 

MEX3C

Mex-3 homolog C (Caenorhabditis elegans)

 

NKRF

NFKB repressing factor

[40]

NONO

Non-POU domain containing, octamer-binding

[41, 42]

PHF6

PHD finger protein 6

[43–45]

RBM10

RNA-binding motif protein 10

 

RBM3

RNA-binding motif (RNP1, RRM) protein 3

[46–49]

RBMX

RNA-binding motif protein, X-linked

[50]

RBMX2

RNA-binding motif protein, X-linked 2

 

RPGR

Retinitis pigmentosa GTPase regulator

 

RPL10

Ribosomal protein L10

 

RPS4X

Ribosomal protein S4, X-linked

 

SLC25A5

Solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

 

UBA1

Ubiquitin-like modifier activating enzyme 1

[51, 52]

UPF3B

UPF3 regulator of nonsense transcripts homolog B (yeast)

 

UTP14A

UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)

Â