Table 2 Description of the datasets of tumor somatic mutations collected and analyzed to detect candidate cancer driver genes

Bladder

BLADDER UROTHELIAL TCGA

Bladder urothelial carcinoma

TCGA

Synapse

98

-

Brain

BRAIN GLIOBASTOMA TCGA

Glioblastoma multiforme

TCGA

Synapse

290

[84]

BRAIN GLIOBASTOMA JHU

Glioblastoma multiforme

John Hopkins University

ICGC DCC

88

[88]

BRAIN PEDIATRIC DKFZ

Pediatric brain tumors

DKFZ

ICGC DCC

113

[89, 90]

Breast

BREAST JHU

Breast cancer

Johns Hopkins University

ICGC DCC

42

[91]

BREAST WTSI

Breast cancer

Welcome Trust/ Sanger Institute

ICGC DCC

100

[56]

BREAST TN UBC

Triple negative breast cancer

University of British Columbia

PubMed

65

[92]

BREAST TCGA

Breast invasive carcinoma

TCGA

Synapse

762

[93]

BREAST BROAD

Breast cancer

BROAD Institute

PubMed

103

[94]

BREAST ER + WU

ER + breast cancer

Washington University

PubMed

77

[38]

Colorectal

COLORECTAL ADENO JHU

Colorectal adenocarcinoma

Johns Hopkins University

ICGC DCC

36

[91]

COLORECTAL ADENO TCGA

Colorectal adenocarcinoma

TCGA

Synapse

193

[28]

Head and neck

HEAD/NECK SQUAMOUS BROAD

Head and neck squamous cell carcinoma

Broad Institute

SM

74

[95]

HEAD/NECK SQUAMOUS TCGA

Head and neck squamous cell carcinoma

TCGA

Synapse

301

-

Hematopo-ietic

CLL SPAIN

Chronic lymphocytic leukemia

Spanish Ministry of Science

ICGC DCC

109

[71, 96]

CLL DFCI

Chronic lymphocytic leukemia

Dana Farber Cancer Institute

SM

90

[97]

AML TCGA

Acute myeloid leukemia

TCGA

Synapse

196

[98]

Kidney

KIDNEY CLEAR CELL TCGA

Kidney clear cell carcinoma

TCGA

Synapse

417

[99]

Liver

LIVER IARC

Liver cancer

IACR

ICGC DCC

24

[100]

Lung

LUNG ADENO WU

Lung adenocarcinoma

Washington University School of Medicine

ICGC DCC

162

[101]

LUNG NON SMALL CELL MCW

Non small cell lung cancer

Medical College of Wisconsin

SM

31

[37]

LUNG SQUAMOUS TCGA

Lung squamous cell carcinoma

TCGA

Synapse

174

[102]

LUNG ADENO TCGA

Lung adenocarcinoma

TCGA

Synapse

228

-

LUNG SMALL CELL UCOLOGNE

Small cell lung cancer

University Cologne

SM

27

[58]

LUNG SMALL CELL JHU

Small cell lung cancer

Johns Hopkins University

SM

42

[103]

Ovary

OVARY TCGA

Ovarian serous cystadenocarcinoma

TCGA

Synapse

316

[104]

Pancreas

PANCREAS JHU

Pancreatic cancer

Johns Hopkins University

ICGC DCC

114

[105]

PANCREAS OICR

Pancreatic cancer

Ontario Institute for Cancer Research

ICGC DCC

33

[106]

PANCREAS QCMG

Pancreatic cancer

Queensland Centre for Medical Genomics

ICGC DCC

67

[106]

Stomach

GASTRIC PFIZER

Gastric cancer

Pfizer Worldwide Research and Development

SM

22

[107]

Uterus

UTERI TCGA

Uterine corpus endometrioid carcinoma

TCGA

Synapse

230

-