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Table 3 Newly predicted somatic mutations in hemimegalencephaly data.

From: Virmid: accurate detection of somatic mutations with sample impurity inference

Subject Estimated α (standard deviation) n.Total.Muta Overlapping mutation Novel mutation
    n.Mutb n.Exonc n.Misd Gene n.Mutb n.Exonc n.Misd Gene
HME-1563 77.9% (±0.006) 478 108 54 33 MTOR 370 209 147  
HME-1565 71.3% (±0.003) 494 124 78 50 AKT3 370 72 43  
HME-1573 64.0% (±0.017) 542 235 167 112 PIK3CA 307 301 185  
HME-1574 83.4% (±0.005) 579 100 63 34   479 412 281 MTOR
HME-1620 84.8% (±0.004) 694 86 56 27   608 383 267  
  1. an.Total.Mut is the number of all called mutations.
  2. bn.Mut is the number of (overlapping or novel) mutations. One mutation loci may be counted multiple times when more than one genetic product exists at the position.
  3. cn.Exon is the number of mutations in an exon.
  4. dn.Mis is the number of missense (or nonsense) mutations.