αa
|
n.Answerb
|
Coverage = 40 ×
|
Coverage = 100 ×
|
---|
| |
n.Predictc
|
n.Correctd
|
Precision
|
Recall
|
F-score
|
n.Predictc
|
n.Correctd
|
Precision
|
Recall
|
F-score
|
---|
70%
| |
1999
|
1976
|
0.98
|
0.87
|
0.93
|
2208
|
2198
|
1.00e
|
0.97
|
0.98
|
80%
|
2265
|
1551
|
1516
|
0.98
|
0.67
|
0.79
|
2142
|
2133
|
1.00f
|
0.94
|
0.97
|
90%
| |
638
|
611
|
0.96
|
0.27
|
0.42
|
1572
|
1545
|
0.98
|
0.68
|
0.81
|
- Precision and recall values are compared between two different coverages (40 × and 100 ×) at highly contaminated data (α = 70%, 80%, and 90%). Much deeper coverage is required when severe contamination is expected.
- aα is the proportion of the control sample in the disease sample (contamination level).
- bn.Answer is the number of true somatic mutations.
- cn.Predict is the number of mutations predicted by Virmid.
- dn.Correct is the number of correct mutations in the prediction.
- eRounded up from 0.9954.
- fRounded up from 0.9958.