From: Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function
 | Binomial test | Hypergeometric test | |||
---|---|---|---|---|---|
Biological process | Raw P-valuea | FDR Q-valueb | Fold enrichmentc | FDR Q-valued | Fold enrichmente |
Genes enriched with adult-only 5hmC blocks | Â | Â | Â | Â | Â |
    Nuclear-transcribed mRNA catabolic process | 4.30E-182 | 3.22E-180 | 2.49 | 8.82E-03 | 1.16 |
    mRNA catabolic process | 8.88E-165 | 5.52E-163 | 2.25 | 1.77E-02 | 1.14 |
    Carbohydrate transport | 3.29E-125 | 1.51E-123 | 2.06 | 5.91E-03 | 1.15 |
    Vesicle localization | 9.48E-113 | 4.05E-111 | 2.20 | 3.73E-02 | 1.16 |
    Fatty acid oxidation | 5.52E-102 | 2.12E-100 | 2.22 | 4.59E-03 | 1.20 |
    Lipid oxidation | 1.44E-100 | 5.39E-99 | 2.20 | 3.97E-03 | 1.20 |
    mRNA 3'-end processing | 1.73E-98 | 6.27E-97 | 2.24 | 1.11E-02 | 1.17 |
    Monocarboxylic acid catabolic process | 1.35E-95 | 4.80E-94 | 2.21 | 5.31E-03 | 1.20 |
    RNA 3'-end processing | 2.92E-94 | 1.02E-92 | 2.07 | 2.13E-02 | 1.15 |
    Fatty acid catabolic process | 2.99E-90 | 9.99E-89 | 2.22 | 1.00E-02 | 1.20 |
Genes enriched with fetal-only 5hmC blocks | Â | Â | Â | Â | Â |
    Regulation of granulocyte differentiation | 5.88E-23 | 2.45E-20 | 6.20 | 3.56E-02 | 2.58 |
    Regulation of myeloid cell differentiation | 9.74E-17 | 1.67E-14 | 2.19 | 1.84E-03 | 1.64 |
    Induction of apoptosis by extracellular signals | 5.49E-15 | 7.18E-13 | 2.18 | 9.28E-03 | 1.54 |
    Positive regulation of steroid metabolic process | 1.76E-12 | 1.61E-10 | 3.87 | 9.82E-03 | 2.37 |
    Stem cell development | 6.00E-12 | 5.05E-10 | 2.09 | 4.16E-04 | 2.06 |
    Establishment or maintenance of cell polarity | 9.26E-11 | 6.14E-09 | 2.02 | 1.97E-02 | 1.63 |
    Regulation of protein binding | 6.32E-10 | 3.38E-08 | 2.03 | 2.36E-02 | 1.64 |
    Stem cell maintenance | 8.22E-10 | 4.31E-08 | 2.00 | 9.44E-04 | 2.04 |
    Somatic stem cell maintenance | 6.28E-09 | 2.59E-07 | 2.15 | 2.15E-02 | 2.04 |
    Negative regulation of lipoprotein particle clearance | 1.99E-07 | 6.11E-06 | 6.52 | 3.08E-02 | 3.73 |