From: A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
Protein coding gene | C57BL/6J amino acid | C57BL/6N amino acid | SNP is private to: | PROVEAN prediction (score)b | MP terms | B6J versus B6N2 | B6N versus B6Jc |
---|---|---|---|---|---|---|---|
Adcy5 | Valine (V) | Methionine (M) | B6N |
Tolerated (-1.712) | Impaired coordination_MP:0001405 | NR | P |
Hypoactivity_MP:0001402 | NR | P | |||||
Pmch | Isoleucine (I) | Threonine (T) | B6N | Tolerated (0.493) | Decreased circulating glucose level_MP:0005560 | NR | A |
Abnormal glucose tolerance_MP:0005291 | NR | A | |||||
Increased oxygen consumption_MP:0005289 | NR | P | |||||
Pdzk1 | Asparagine (N) | Aspartic Acid (D) | B6J | Tolerated (0.95) | Increased circulating cholesterol level_MP:0001556 | A | NR |
Nlrp12 |
Lysine (K) |
Arginine (A) | B6J | Tolerated (0.781) | Abnormal type IV hypersensitivity reaction_MP:0002534 | P | NR |
Crb1 | - | - | B6N | - | Photosensitivity_MP:0001999 | NR | P |
Abnormal ocular fundus morphology_MP:0002864 | NR | P | |||||
Retinal degeneration_MP:0001326 | NR | P | |||||
Abnormal retinal morphology_MP:0001325 | NR | P | |||||
Abnormal retinal photoreceptor layer_MP:0003728 | NR | P | |||||
Chl1 | - | - | B6J | - | Abnormal learning/memory_ MP:0001449 | A | NR |
Abnormal spatial working memory_MP:0008428 | A | NR | |||||
Rptor | - | - | B6J | - | Increased lean body mass_MP:0003960 | P | NR |
Increased oxygen consumption_MP:0005289 | A | NR | |||||
Hypoactivity_MP:0001402 | A | NR | |||||
Decreased circulating glucose level_MP:0005560 | P | NR | |||||
Improved glucose tolerance_MP:0005292 | A | NR | |||||
Nnt | - | - | B6J | - | Impaired glucose tolerance_MP:0005293 | P | NR |