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Table 1 Overview of the blood samples analyzed using NGS and RT-qPCR

From: A blood based 12-miRNA signature of Alzheimer disease patients

Sample group N Age (mean ± SD) Sex (female/male) MMSE (mean ± SD) Cohort size
NGS
Cohort size
RT-qPCR
AD 106 72.7(10.4) 53/53 18.9 (3.4) 48 94
Healthy control 22 67.1 (7.5) 11/11 29.3 (1.2) 22 21
Mild cognitive impairment 18 73.9 (6.2) 9/9 25.3 (1.4) - 18
Multiple sclerosis 16 32.3 (10.7) 12/4 NA - 16
PD 9 69.7 (9.0) 1/8 25.2 (4.2) - 9
DEP 15 45.2 (9.1) 0/15 NA - 15
BD 15 41.9 (13.7) 14/1 29.5 (1.6) - 15
SCHIZ 14 41.7 (7.9) 1/13 26.1 (4.3) - 14
  1. AD: Alzheimer disease; BD: bipolar disorder; DEP: major depression; MMSE: Mini-Mental State Exam; NA: not available; NGS: next-generation sequencing; PD: Parkinson's disease; RT-qPCR: quantitative real-time PCR; SCHIZ: schizophrenia.