Table 1 Overview of the blood samples analyzed using NGS and RT-qPCR
From: A blood based 12-miRNA signature of Alzheimer disease patients
Sample group | N | Age (mean ± SD) | Sex (female/male) | MMSE (mean ± SD) | Cohort size NGS | Cohort size RT-qPCR |
|---|---|---|---|---|---|---|
AD | 106 | 72.7(10.4) | 53/53 | 18.9 (3.4) | 48 | 94 |
Healthy control | 22 | 67.1 (7.5) | 11/11 | 29.3 (1.2) | 22 | 21 |
Mild cognitive impairment | 18 | 73.9 (6.2) | 9/9 | 25.3 (1.4) | - | 18 |
Multiple sclerosis | 16 | 32.3 (10.7) | 12/4 | NA | - | 16 |
PD | 9 | 69.7 (9.0) | 1/8 | 25.2 (4.2) | - | 9 |
DEP | 15 | 45.2 (9.1) | 0/15 | NA | - | 15 |
BD | 15 | 41.9 (13.7) | 14/1 | 29.5 (1.6) | - | 15 |
SCHIZ | 14 | 41.7 (7.9) | 1/13 | 26.1 (4.3) | - | 14 |