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Table 3 Gene Ontology terms associated with temporal gene expression profiles during excystation

From: The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation

Profile/clustera

GO category name

Fold enrichmentb

Corrected P-valuec

Profile 45

Protein binding

3.1

0.002

 

Catalytic activity

3.4

0.002

 

Metabolic process

3.4

0.05

Cluster (profiles 49, 40, 41, 37, 48, 44)

Zinc ion binding

1.7

<0.001

 

Catalytic activity

1.7

<0.001

 

Pyridoxal phosphate binding

3.7

0.024

 

Nucleic acid binding

1.6

0.028

 

Heat shock protein binding

3

0.032

Profile 49

Helicase activity

4.3

0.042

 

Ubiquitin-dependent protein catabolic process

4.1

0.05

Profile 40

Binding

2.1

0.01

 

Zinc ion binding

2

0.038

Profile 41

Membrane

3.7

0.006

Profile 37

Protein binding

2.4

0.022

 

Catalytic activity

2.5

0.048

Profile 47

Oxidoreductase activity

6.3

0.018

Cluster (profiles 0, 4, 7, 8, 11, 15, 16, 17, 18)

Ribosome

3.7

<0.001

 

Structural constituent of ribosome

3.6

<0.001

 

Translation

3.1

<0.001

 

Intracellular

1.5

<0.001

 

DNA binding

2.1

<0.001

 

Nucleosome

5.6

<0.001

 

Nucleus

2.1

<0.001

 

Nucleosome assembly

4

0.002

 

Signal transduction

1.6

0.024

 

Threonine-type endopeptidase activity

4.2

0.044

 

Proteasome core complex

4.2

0.044

 

Proteolysis involved in cellular protein catabolic process

4.2

0.044

Profile 17

Ribosome

7.1

<0.001

 

Structural constituent of ribosome

6.8

<0.001

 

Translation

6.3

<0.001

 

Intracellular

1.9

0.002

Profile 18

Intracellular

2.1

0.006

 

Ribosome

5

0.006

 

Structural constituent of ribosome

4.8

0.008

 

Translation

4.2

0.02

 

Signal transduction

3

0.024

Profile 7

Ribosome

5.3

0.002

 

Structural constituent of ribosome

5.1

0.002

 

Translation

4

0.012

 

DNA binding

3.1

0.04

Profile 8

Intracellular

2.3

0.01

 

Protein transport

3.6

0.012

 

GTP binding

3

0.024

 

Catalytic activity

3.2

0.024

 

Small GTPase mediated signal transduction

2.9

0.032

Profile 16

DNA binding

4.4

<0.001

  1. aSee Figure 4 and Additional file 8 for profiles/clusters. bRatio of the observed number of genes with associated GO term to the number expected for a profile of the same size. cP-value Bonferroni-corrected for multiple tests.