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Table 3 Gene Ontology terms associated with temporal gene expression profiles during excystation

From: The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation

Profile/clustera GO category name Fold enrichmentb Corrected P-valuec
Profile 45 Protein binding 3.1 0.002
  Catalytic activity 3.4 0.002
  Metabolic process 3.4 0.05
Cluster (profiles 49, 40, 41, 37, 48, 44) Zinc ion binding 1.7 <0.001
  Catalytic activity 1.7 <0.001
  Pyridoxal phosphate binding 3.7 0.024
  Nucleic acid binding 1.6 0.028
  Heat shock protein binding 3 0.032
Profile 49 Helicase activity 4.3 0.042
  Ubiquitin-dependent protein catabolic process 4.1 0.05
Profile 40 Binding 2.1 0.01
  Zinc ion binding 2 0.038
Profile 41 Membrane 3.7 0.006
Profile 37 Protein binding 2.4 0.022
  Catalytic activity 2.5 0.048
Profile 47 Oxidoreductase activity 6.3 0.018
Cluster (profiles 0, 4, 7, 8, 11, 15, 16, 17, 18) Ribosome 3.7 <0.001
  Structural constituent of ribosome 3.6 <0.001
  Translation 3.1 <0.001
  Intracellular 1.5 <0.001
  DNA binding 2.1 <0.001
  Nucleosome 5.6 <0.001
  Nucleus 2.1 <0.001
  Nucleosome assembly 4 0.002
  Signal transduction 1.6 0.024
  Threonine-type endopeptidase activity 4.2 0.044
  Proteasome core complex 4.2 0.044
  Proteolysis involved in cellular protein catabolic process 4.2 0.044
Profile 17 Ribosome 7.1 <0.001
  Structural constituent of ribosome 6.8 <0.001
  Translation 6.3 <0.001
  Intracellular 1.9 0.002
Profile 18 Intracellular 2.1 0.006
  Ribosome 5 0.006
  Structural constituent of ribosome 4.8 0.008
  Translation 4.2 0.02
  Signal transduction 3 0.024
Profile 7 Ribosome 5.3 0.002
  Structural constituent of ribosome 5.1 0.002
  Translation 4 0.012
  DNA binding 3.1 0.04
Profile 8 Intracellular 2.3 0.01
  Protein transport 3.6 0.012
  GTP binding 3 0.024
  Catalytic activity 3.2 0.024
  Small GTPase mediated signal transduction 2.9 0.032
Profile 16 DNA binding 4.4 <0.001
  1. aSee Figure 4 and Additional file 8 for profiles/clusters. bRatio of the observed number of genes with associated GO term to the number expected for a profile of the same size. cP-value Bonferroni-corrected for multiple tests.