Table 2 Gene Ontology terms associated with temporal gene expression profiles during encystation
From: The genome and transcriptome of the enteric parasite Entamoeba invadens, a model for encystation
| Profile/clustera | GO category name | Fold enrichmentb | Corrected P-valuec |
|---|---|---|---|
| Profile 16 | Translation | 7.8 | <0.001 |
| Structural constituent of ribosome | 7.9 | <0.001 | |
| Ribosome | 8.1 | <0.001 | |
| Protein binding | 2.9 | <0.001 | |
| Actin binding | 4.9 | <0.001 | |
| Glycolysis | 12.2 | <0.001 | |
| Intracellular | 1.7 | <0.001 | |
| Cytoplasm | 4 | 0.002 | |
| Catalytic activity | 2.3 | 0.002 | |
| Oxidoreductase activity | 3.4 | 0.002 | |
| Oxidation-reduction process | 4 | 0.038 | |
| Profile 15 | Translation | 12.1 | <0.001 |
| Structural constituent of ribosome | 11.8 | <0.001 | |
| Ribosome | 11 | <0.001 | |
| Small ribosomal subunit | 24.3 | <0.001 | |
| Intracellular | 2.2 | <0.001 | |
| Aminoacyl-tRNA ligase activity | 16.6 | <0.001 | |
| tRNA aminoacylation for protein translation | 16.6 | <0.001 | |
| Cytoplasm | 6.5 | <0.001 | |
| NAD binding | 16.5 | <0.001 | |
| Metabolic process | 3 | 0.018 | |
| Cluster (profiles 24, 41) | Heat shock protein binding | 6.7 | 0.004 |
| Profile 24 | Heat shock protein binding | 8.5 | 0.006 |
| Unfolded protein binding | 6.3 | 0.01 | |
| Protein folding | 5.7 | 0.014 | |
| Cluster (profiles 31, 34) | Metabolic process | 3.4 | <0.001 |
| Catalytic activity | 2.5 | <0.001 | |
| Binding | 2.3 | <0.001 | |
| Phosphatidylcholine-sterol O-acyltransferase activity | 9 | 0.016 | |
| Membrane coat | 5.8 | 0.016 | |
| Structural molecule activity | 6.8 | 0.018 | |
| Vesicle-mediated transport | 3.3 | 0.04 | |
| Profile 31 | Metabolic process | 3.5 | <0.001 |
| Catalytic activity | 2.6 | <0.001 | |
| Binding | 2.4 | <0.001 | |
| Membrane coat | 6.8 | 0.002 | |
| Phosphatidylcholine-sterol O-acyltransferase activity | 10.5 | 0.002 | |
| Structural molecule activity | 7.9 | 0.002 | |
| Vesicle-mediated transport | 3.9 | 0.004 | |
| Lipid metabolic process | 4.9 | 0.034 | |
| Profile 19 | Vesicle-mediated transport | 5.1 | 0.062 |
| Nucleic acid binding | 2.2 | 0.464 | |
| Profile 21 | Integral to membrane | 4.7 | 0.014 |
| Membrane | 4.1 | 0.038 | |
| Profile 20 | Hydrolase activity | 4 | 0.014 |
| Cluster (profiles 32 13) | Methionine adenosyltransferase activity | 30.5 | <0.001 |
| One carbon metabolic process | 30.5 | <0.001 | |
| DNA binding | 3.6 | <0.001 | |
| Nucleosome | 12.2 | 0.002 | |
| Nucleus | 3 | 0.002 | |
| Nucleosome assembly | 8 | 0.002 | |
| Sequence-specific DNA binding | 6.9 | 0.034 | |
| Profile 32 | Methionine adenosyltransferase activity | 48.7 | <0.001 |
| One carbon metabolic process | 48.7 | <0.001 | |
| DNA binding | 3.8 | <0.001 | |
| Nucleus | 3.3 | 0.01 | |
| Profile 13 | Intracellular protein transport | 5.3 | 0.002 |
| Intracellular | 2.3 | 0.002 | |
| GTP binding | 3.3 | 0.002 | |
| Small GTPase mediated signal transduction | 3.1 | 0.002 | |
| Protein transport | 3.4 | 0.004 | |
| Nucleocytoplasmic transport | 5.6 | 0.016 | |
| GTPase activity | 4.3 | 0.036 |
