From: VlincRNAs controlled by retroviral elements are a hallmark of pluripotency and cancer
Source | Cell line/Tissue | Cell Type | Number of vlincRNAs | VlincRNAs Overlapping with All Promoters | Overlap Expected by Chance | Fold over chance | p-value |
---|---|---|---|---|---|---|---|
Kapranov et al[12] | K562 + Ewing Sarcomas | Malignant | 580 | 336* | 131.7 | 2.5 | 2.4E-74 |
This work | Blood | Normal Tissue | 613 | 321* | 142.5 | 2.2 | 7.7E-55 |
ENCODE | K562 | Malignant | 407 | 216** | 23.2 | 9.3 | 1.3E-153 |
ENCODE | HepG2 | Malignant | 501 | 192** | 34.1 | 5.6 | 7.5E-91 |
ENCODE | HeLaS3 | Malignant | 206 | N/D | N/D | N/D | N/D |
ENCODE | GM12878 | Immortalized | 591 | 128** | 27.5 | 4.6 | 3.6E-48 |
ENCODE | NHEK | Primary | 248 | 51** | 12.1 | 4.2 | 2.28 E-18 |
ENCODE | HUVEC | Primary | 340 | 86** | 13.1 | 6.5 | 1.9E-44 |
ENCODE | H1-hEsc | Embryonic Stem | 469 | 205** | 24.9 | 8.2 | 1.9E-130 |
This work | Mouse Lung | Normal Tissue | 225 | 115* | 49.3 | 2.3 | 7.6E-22 |